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Steroids are the fastest-acting and most potent
drugs used to treat inflammation. There are several types of steroids,
common ones being DEXAMETHASONE, PREDNISOLONE, PREDNISONE, METHYLPREDNISOLONE,
BETAMETHASONE, and TRIAMCINOLONE.
Steroids may be given in many forms, including
eyedrops, injections, pills or intravenously (IV). Eyedrops are
used to treat some ocular surface inflammation and inflammation
in the front of the eye such as IRITIS. When the inflammation is
deeper in the eye, steroid injections around the eye or even directly
into the eye may be necessary. Oral or IV steroid therapy may be
necessary when treating SCLERITIS, PERIPHERAL ULCERATIVE KERATITIS,
and severe UVEITIS and RETINAL VASCULITIS.
Steroids have many systemic side effects. Almost
every organ system is affected by steroid therapy, and long term
use of steroids can cause the weakening of the bones, thinning of
the skin, diabetes, weight gain and changes in fat distribution
around the body, to name only a few problems. Steroid therapy also
has ocular side effects, including cataracts and elevation in intraocular
pressure. For this reason, long term steroid therapy should be avoided
whenever possible.
In patients with ocular inflammation, the risks
of steroid therapy are always weighed against the risk of not using
these drugs to treat the active disease. Generally, in the short
term, steroid therapy causes fewer problems than does ocular inflammation,
and so judicious use of these drugs is safe and very effective for
patients who need them.
The Medline plus website of the National Library
of Medicine has excellent information on CORTICOSTEROID
EYEDROPS and SYSTEMIC
CORTICOSTEROIDS.
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